Emasculate

e·mas·cu·late  

tr.v. e·mas·cu·lat·ed, e·mas·cu·lat·ing, e·mas·cu·lates
1. To castrate.
2. To deprive of strength or vigor; weaken.
adj. (-lt)
Deprived of virility, strength, or vigor.

In his 30 years of rule as President, the 82 year old Hosni Mubarak ensured that all opposition was decimated or emasculated